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Altered efficacy of AT1R-targeted treatment after spontaneous cancer cell-AT1R upregulation
BACKGROUND: Targeting of the renin angiotensin system (RAS) reduces tumour growth in experimental models of cancer. We aimed to establish if combined targeting of the 'classical' and 'alternative' arms of the RAS could result in synergistic inhibition of colorectal cancer (CRC) l...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141779/ https://www.ncbi.nlm.nih.gov/pubmed/21703011 http://dx.doi.org/10.1186/1471-2407-11-274 |