Nimesulide inhibits protein kinase C epsilon and substance P in sensory neurons – comparison with paracetamol

In this paper we describe new actions of nimesulide and paracetamol in cultured peripheral neurons isolated from rat dorsal root ganglia (DRG). Both drugs were able to decrease in a dose-dependent fashion the number of cultured DRG neurons showing translocation of protein kinase C epsilon (PKCɛ) cau...

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Detalles Bibliográficos
Autores principales: Vellani, Vittorio, Franchi, Silvia, Prandini, Massimiliano, Moretti, Sarah, Pavesi, Giorgia, Giacomoni, Chiara, Sacerdote, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141834/
https://www.ncbi.nlm.nih.gov/pubmed/21811393
http://dx.doi.org/10.2147/JPR.S21931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141834/
https://www.ncbi.nlm.nih.gov/pubmed/21811393
http://dx.doi.org/10.2147/JPR.S21931

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