Formulation and pharmacokinetic evaluation of a paclitaxel nanosuspension for intravenous delivery

Paclitaxel is a diterpenoid isolated from Taxus brevifolia. It is effective for various cancers, especially ovarian and breast cancer. Due to its aqueous insolubility, it is administered dissolved in ethanol and Cremophor(®) EL (BASF, Ludwigshafen, Germany), which can cause serious allergic reaction...

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Detalles Bibliográficos
Autores principales: Wang, Yonglu, Li, Xueming, Wang, Liyao, Xu, Yuanlong, Cheng, Xiaodan, Wei, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141875/
https://www.ncbi.nlm.nih.gov/pubmed/21796250
http://dx.doi.org/10.2147/IJN.S21097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141875/
https://www.ncbi.nlm.nih.gov/pubmed/21796250
http://dx.doi.org/10.2147/IJN.S21097

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