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Endothelin-1 Reduces Glucose Uptake in Human Skeletal Muscle In Vivo and In Vitro

OBJECTIVE: Endothelin (ET)-1 is a vasoconstrictor and proinflammatory peptide that may interfere with glucose uptake. Our objective was to investigate whether exogenous ET-1 affects glucose uptake in the forearm of individuals with insulin resistance and in cultured human skeletal muscle cells. RESE...

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Detalles Bibliográficos
Autores principales: Shemyakin, Alexey, Salehzadeh, Firoozeh, Esteves Duque-Guimaraes, Daniella, Böhm, Felix, Rullman, Eric, Gustafsson, Thomas, Pernow, John, Krook, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142065/
https://www.ncbi.nlm.nih.gov/pubmed/21677282
http://dx.doi.org/10.2337/db10-1281