High-Fat Diet–Induced Adipocyte Cell Death Occurs Through a Cyclophilin D Intrinsic Signaling Pathway Independent of Adipose Tissue Inflammation

OBJECTIVE: Previous studies have demonstrated that mice fed a high-fat diet (HFD) develop insulin resistance with proinflammatory macrophage infiltration into white adipose tissue. Concomitantly, adipocytes undergo programmed cell death with the loss of the adipocyte-specific lipid droplet protein p...

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Detalles Bibliográficos
Autores principales: Feng, Daorong, Tang, Yan, Kwon, Hyokjoon, Zong, Haihong, Hawkins, Meredith, Kitsis, Richard N., Pessin, Jeffrey E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Immunology and Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142076/
https://www.ncbi.nlm.nih.gov/pubmed/21734017
http://dx.doi.org/10.2337/db10-1411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142076/
https://www.ncbi.nlm.nih.gov/pubmed/21734017
http://dx.doi.org/10.2337/db10-1411

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