Cargando…

Multidimensional Single Cell Based STAT Phosphorylation Profiling Identifies a Novel Biosignature for Evaluation of Systemic Lupus Erythematosus Activity

INTRODUCTION: Dysregulated cytokine action on immune cells plays an important role in the initiation and progress of systemic lupus erythematosus (SLE), a complex autoimmune disease. Comprehensively quantifying basal STATs phosphorylation and their signaling response to cytokines should help us to b...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Xinfang, Guo, Yanzhi, Bao, Chunde, Shen, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142107/
https://www.ncbi.nlm.nih.gov/pubmed/21799742
http://dx.doi.org/10.1371/journal.pone.0021671