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Sensitive and Specific Fluorescent Probes for Functional Analysis of the Three Major Types of Mammalian ABC Transporters

An underlying mechanism for multi drug resistance (MDR) is up-regulation of the transmembrane ATP-binding cassette (ABC) transporter proteins. ABC transporters also determine the general fate and effect of pharmaceutical agents in the body. The three major types of ABC transporters are MDR1 (P-gp, P...

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Detalles Bibliográficos
Autores principales: Lebedeva, Irina V., Pande, Praveen, Patton, Wayne F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142157/
https://www.ncbi.nlm.nih.gov/pubmed/21799851
http://dx.doi.org/10.1371/journal.pone.0022429