siRNA Knockdown of Ribosomal Protein Gene RPL19 Abrogates the Aggressive Phenotype of Human Prostate Cancer

We provide novel functional data that posttranscriptional silencing of gene RPL19 using RNAi not only abrogates the malignant phenotype of PC-3M prostate cancer cells but is selective with respect to transcription and translation of other genes. Reducing RPL19 transcription modulates a subset of gen...

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Detalles Bibliográficos
Autores principales: Bee, Alix, Brewer, Daniel, Beesley, Carol, Dodson, Andrew, Forootan, Shiva, Dickinson, Timothy, Gerard, Patricia, Lane, Brian, Yao, Sheng, Cooper, Colin S., Djamgoz, Mustafa B. A., Gosden, Christine M., Ke, Youqiang, Foster, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142177/
https://www.ncbi.nlm.nih.gov/pubmed/21799931
http://dx.doi.org/10.1371/journal.pone.0022672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142177/
https://www.ncbi.nlm.nih.gov/pubmed/21799931
http://dx.doi.org/10.1371/journal.pone.0022672

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