Specific antibody-receptor interactions trigger InlAB-independent uptake of listeria monocytogenes into tumor cell lines

BACKGROUND: Specific cell targeting is an important, yet unsolved problem in bacteria-based therapeutic applications, like tumor or gene therapy. Here, we describe the construction of a novel, internalin A and B (InlAB)-deficient Listeria monocytogenes strain (Lm-spa(+)), which expresses protein A o...

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Detalles Bibliográficos
Autores principales: Heisig, Martin, Frentzen, Alexa, Bergmann, Birgit, Galmbacher, Katharina, Gentschev, Ivaylo, Hotz, Christian, Schoen, Christoph, Stritzker, Jochen, Fensterle, Joachim, Rapp, Ulf R, Goebel, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142209/
https://www.ncbi.nlm.nih.gov/pubmed/21745384
http://dx.doi.org/10.1186/1471-2180-11-163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142209/
https://www.ncbi.nlm.nih.gov/pubmed/21745384
http://dx.doi.org/10.1186/1471-2180-11-163

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