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Specific antibody-receptor interactions trigger InlAB-independent uptake of listeria monocytogenes into tumor cell lines
BACKGROUND: Specific cell targeting is an important, yet unsolved problem in bacteria-based therapeutic applications, like tumor or gene therapy. Here, we describe the construction of a novel, internalin A and B (InlAB)-deficient Listeria monocytogenes strain (Lm-spa(+)), which expresses protein A o...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142209/ https://www.ncbi.nlm.nih.gov/pubmed/21745384 http://dx.doi.org/10.1186/1471-2180-11-163 |