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The asthma candidate gene NPSR1 mediates isoform specific downstream signalling

BACKGROUND: Neuropeptide S Receptor 1 (NPSR1, GPRA, GPR154) was first identified as an asthma candidate gene through positional cloning and has since been replicated as an asthma and allergy susceptibility gene in several independent association studies. In humans, NPSR1 encodes two G protein-couple...

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Detalles Bibliográficos
Autores principales: Pietras, Christina Orsmark, Vendelin, Johanna, Anedda, Francesca, Bruce, Sara, Adner, Mikael, Sundman, Lilli, Pulkkinen, Ville, Alenius, Harri, D'Amato, Mauro, Söderhäll, Cilla, Kere, Juha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142248/
https://www.ncbi.nlm.nih.gov/pubmed/21707994
http://dx.doi.org/10.1186/1471-2466-11-39