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A computational approach to candidate gene prioritization for X-linked mental retardation using annotation-based binary filtering and motif-based linear discriminatory analysis

BACKGROUND: Several computational candidate gene selection and prioritization methods have recently been developed. These in silico selection and prioritization techniques are usually based on two central approaches - the examination of similarities to known disease genes and/or the evaluation of fu...

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Detalles Bibliográficos
Autores principales: Lombard, Zané, Park, Chungoo, Makova, Kateryna D, Ramsay, Michèle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142252/
https://www.ncbi.nlm.nih.gov/pubmed/21668950
http://dx.doi.org/10.1186/1745-6150-6-30