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The prognostic value of p53 mutation in pediatric marrow hypoplasia
BACKGROUND: The tumor suppressor gene p53 is involved in the control of cell proliferation, particularly in stressed cells. p 53 gene mutations are the most frequent genetic event found in human cancers. Fanconi Anemia (FA) is the most common representative of inherited bone marrow failure syndromes...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142480/ https://www.ncbi.nlm.nih.gov/pubmed/21718492 http://dx.doi.org/10.1186/1746-1596-6-58 |