Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ)

BACKGROUND: Overproduction of proinflammatory cytokines from activated microglia has been implicated as an important contributor to pathophysiology progression in both acute and chronic neurodegenerative diseases. Therefore, it is critical to elucidate intracellular signaling pathways that are signi...

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Detalles Bibliográficos
Autores principales: Bachstetter, Adam D, Xing, Bin, de Almeida, Lucia, Dimayuga, Edgardo R, Watterson, D Martin, Van Eldik, Linda J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142505/
https://www.ncbi.nlm.nih.gov/pubmed/21733175
http://dx.doi.org/10.1186/1742-2094-8-79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142505/
https://www.ncbi.nlm.nih.gov/pubmed/21733175
http://dx.doi.org/10.1186/1742-2094-8-79

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