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Metformin as an energy restriction mimetic agent for breast cancer prevention

BACKGROUND: This study examined whether metformin administration inhibited chemically induced mammary carcinogenesis in rats. In cancer prevention, metformin may act (1) indirectly through reducing systemic risk factors; or (2) directly through AMPK-mediated signaling. To begin to delineate clinical...

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Detalles Bibliográficos
Autores principales: Zhu, Zongjian, Jiang, Weiqin, Thompson, Matthew D., McGinley, John N., Thompson, Henry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142764/
https://www.ncbi.nlm.nih.gov/pubmed/21799661