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Metformin as an energy restriction mimetic agent for breast cancer prevention

BACKGROUND: This study examined whether metformin administration inhibited chemically induced mammary carcinogenesis in rats. In cancer prevention, metformin may act (1) indirectly through reducing systemic risk factors; or (2) directly through AMPK-mediated signaling. To begin to delineate clinical...

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Detalles Bibliográficos
Autores principales:	Zhu, Zongjian, Jiang, Weiqin, Thompson, Matthew D., McGinley, John N., Thompson, Henry J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142764/ https://www.ncbi.nlm.nih.gov/pubmed/21799661

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