Molecular alterations associated with liver metastases development in colorectal cancer patients

BACKGROUND: Understanding the molecular biology of colorectal cancer (CRC) provides opportunities for effective personalised patient management. We evaluated whether chromosomal aberrations, mutations in the PI(3)K signalling pathway and the CpG-island methylator phenotype (CIMP) in primary colorect...

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Detalles Bibliográficos
Autores principales: Bruin, S C, He, Y, Mikolajewska-Hanclich, I, Liefers, G-J, Klijn, C, Vincent, A, Verwaal, V J, de Groot, K A, Morreau, H, van Velthuysen, M-L F, Tollenaar, R A E M, van ‘t Veer, L J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142796/
https://www.ncbi.nlm.nih.gov/pubmed/21673680
http://dx.doi.org/10.1038/bjc.2011.184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142796/
https://www.ncbi.nlm.nih.gov/pubmed/21673680
http://dx.doi.org/10.1038/bjc.2011.184

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