Quercetin downregulates Mcl-1 by acting on mRNA stability and protein degradation

BACKGROUND: We recently demonstrated that quercetin, a flavonoid naturally present in food and beverages belonging to the large class of phytochemicals, was able to sensitise leukaemic cells isolated from patients with chronic lymphocytic leukaemia (CLL) when associated with recombinant tumour necro...

Descripción completa

Detalles Bibliográficos
Autores principales: Spagnuolo, C, Cerella, C, Russo, M, Chateauvieux, S, Diederich, M, Russo, G L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142809/
https://www.ncbi.nlm.nih.gov/pubmed/21750559
http://dx.doi.org/10.1038/bjc.2011.229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142809/
https://www.ncbi.nlm.nih.gov/pubmed/21750559
http://dx.doi.org/10.1038/bjc.2011.229

Ejemplares similares