Inferring Gene-Phenotype Associations via Global Protein Complex Network Propagation

BACKGROUND: Phenotypically similar diseases have been found to be caused by functionally related genes, suggesting a modular organization of the genetic landscape of human diseases that mirrors the modularity observed in biological interaction networks. Protein complexes, as molecular machines that...

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Detalles Bibliográficos
Autores principales: Yang, Peng, Li, Xiaoli, Wu, Min, Kwoh, Chee-Keong, Ng, See-Kiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143124/
https://www.ncbi.nlm.nih.gov/pubmed/21799737
http://dx.doi.org/10.1371/journal.pone.0021502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143124/
https://www.ncbi.nlm.nih.gov/pubmed/21799737
http://dx.doi.org/10.1371/journal.pone.0021502

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