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Inferring Gene-Phenotype Associations via Global Protein Complex Network Propagation
BACKGROUND: Phenotypically similar diseases have been found to be caused by functionally related genes, suggesting a modular organization of the genetic landscape of human diseases that mirrors the modularity observed in biological interaction networks. Protein complexes, as molecular machines that...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143124/ https://www.ncbi.nlm.nih.gov/pubmed/21799737 http://dx.doi.org/10.1371/journal.pone.0021502 |