Enhanced Chromatin Accessibility and Recruitment of JUNB Mediate the Sustained IL-4 Expression in NFAT1 Deficient T Helper 2 Cells

Nuclear factor of activated T cells (NFAT) is a family of transcription factors composed of five proteins. Among them, NFAT1 is a predominant NFAT protein in CD4(+) T cells. NFAT1 positively regulates transcription of a large number of inducible cytokine genes including IL-2, IL-4, IL-5 and other cy...

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Detalles Bibliográficos
Autores principales: Son, Jun-Seock, Chae, Chang-Suk, Hwang, Ji-Sun, Park, Zee Yong, Im, Sin-Hyeog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143129/
https://www.ncbi.nlm.nih.gov/pubmed/21799768
http://dx.doi.org/10.1371/journal.pone.0022042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143129/
https://www.ncbi.nlm.nih.gov/pubmed/21799768
http://dx.doi.org/10.1371/journal.pone.0022042

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