New Human Papilloma Virus E2 Transcription Factor Mimics: A Tripyrrole-Peptide Conjugate with Tight and Specific DNA-Recognition

BACKGROUND: Human papillomavirus (HPV) is the main causative agent of cervical cancer, particularly high risk strains such us HPV-16, -18 and -31. The viral encoded E2 protein acts as a transcriptional modulator and exerts a key role in viral DNA replication. Thus, E2 constitutes an attractive targe...

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Detalles Bibliográficos
Autores principales: Wetzler, Diana E., Comin, Maria J., Krajewski, Krzysztof, Gallo, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143144/
https://www.ncbi.nlm.nih.gov/pubmed/21799846
http://dx.doi.org/10.1371/journal.pone.0022409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143144/
https://www.ncbi.nlm.nih.gov/pubmed/21799846
http://dx.doi.org/10.1371/journal.pone.0022409

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