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Runs of Homozygosity Do Not Influence Survival to Old Age

Runs of homozygosity (ROH) are extended tracts of adjacent homozygous single nucleotide polymorphisms (SNPs) that are more common in unrelated individuals than previously thought. It has been proposed that estimating ROH on a genome-wide level, by making use of the genome-wide single nucleotide poly...

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Detalles Bibliográficos
Autores principales: Kuningas, Maris, McQuillan, Ruth, Wilson, James F., Hofman, Albert, van Duijn, Cornelia M., Uitterlinden, André G., Tiemeier, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143169/
https://www.ncbi.nlm.nih.gov/pubmed/21799906
http://dx.doi.org/10.1371/journal.pone.0022580