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Runs of Homozygosity Do Not Influence Survival to Old Age
Runs of homozygosity (ROH) are extended tracts of adjacent homozygous single nucleotide polymorphisms (SNPs) that are more common in unrelated individuals than previously thought. It has been proposed that estimating ROH on a genome-wide level, by making use of the genome-wide single nucleotide poly...
Autores principales: | Kuningas, Maris, McQuillan, Ruth, Wilson, James F., Hofman, Albert, van Duijn, Cornelia M., Uitterlinden, André G., Tiemeier, Henning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143169/ https://www.ncbi.nlm.nih.gov/pubmed/21799906 http://dx.doi.org/10.1371/journal.pone.0022580 |
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