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Amelioration of Lupus Nephritis by Serum Amyloid P Component Gene Therapy with Distinct Mechanisms Varied from Different Stage of the Disease

BACKGROUND: Our previous study revealed that administration of syngeneic female BALB/c mice with excessive self activated lymphocyte-derived DNA (ALD-DNA) could induce systemic lupus erythematosus (SLE) disease, indicating that overload of self-DNA might exceed normal clearance ability and comprise...

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Detalles Bibliográficos
Autores principales: Zhang, Weijuan, Wu, Jin, Qiao, Bin, Xu, Wei, Xiong, Sidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143173/
https://www.ncbi.nlm.nih.gov/pubmed/21799927
http://dx.doi.org/10.1371/journal.pone.0022659