Inhibition of IGF-1 Signalling Enhances the Apoptotic Effect of AS602868, an IKK2 Inhibitor, in Multiple Myeloma Cell Lines

Multiple myeloma (MM) is a B cell neoplasm characterized by bone marrow infiltration with malignant plasma cells. IGF-1 signalling has been explored as a therapeutic target in this disease. We analyzed the effect of the IKK2 inhibitor AS602868, in combination with a monoclonal antibody targeting IGF...

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Detalles Bibliográficos
Autores principales: Tagoug, Ines, Sauty De Chalon, Amélie, Dumontet, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143180/
https://www.ncbi.nlm.nih.gov/pubmed/21799925
http://dx.doi.org/10.1371/journal.pone.0022641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143180/
https://www.ncbi.nlm.nih.gov/pubmed/21799925
http://dx.doi.org/10.1371/journal.pone.0022641

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