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Complex trait analysis of the mouse striatum: independent QTLs modulate volume and neuron number

BACKGROUND: The striatum plays a pivotal role in modulating motor activity and higher cognitive function. We analyzed variation in striatal volume and neuron number in mice and initiated a complex trait analysis to discover polymorphic genes that modulate the structure of the basal ganglia. RESULTS:...

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Detalles Bibliográficos
Autores principales: Rosen, Glenn D, Williams, Robert W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC31432/
https://www.ncbi.nlm.nih.gov/pubmed/11319941
http://dx.doi.org/10.1186/1471-2202-2-5