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Superior Therapeutic Potential of Young Bone Marrow Mesenchymal Stem Cells by Direct Intramyocardial Delivery in Aged Recipients with Acute Myocardial Infarction: In Vitro and In Vivo Investigation

Introduction. Bone-marrow-derived mesenchymal stem cells (MSCs) have been studied for treatment of myocardial infarction (MI). Since MSCs from older donors show quantitative and qualitative senescent changes, we hypothesized that a better outcome may be achieved if aged recipients are given MSCs obt...

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Detalles Bibliográficos
Autores principales: Nayan, Madhur, Paul, Arghya, Chen, Guangyong, Chiu, Ray C. J., Prakash, Satya, Shum-Tim, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143440/
https://www.ncbi.nlm.nih.gov/pubmed/21808722
http://dx.doi.org/10.4061/2011/741213