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Craniosynostosis of Coronal Suture in Twist1(+/−) Mice Occurs Through Endochondral Ossification Recapitulating the Physiological Closure of Posterior Frontal Suture
Craniosynostosis, the premature closure of cranial suture, is a pathologic condition that affects 1/2000 live births. Saethre-Chotzen syndrome is a genetic condition characterized by craniosynostosis. The Saethre-Chotzen syndrome, which is defined by loss-of-function mutations in the TWIST gene, is...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Research Foundation
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143731/ https://www.ncbi.nlm.nih.gov/pubmed/21811467 http://dx.doi.org/10.3389/fphys.2011.00037 |