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Prestin-Driven Cochlear Amplification Is Not Limited by the Outer Hair Cell Membrane Time Constant

Outer hair cells (OHCs) provide amplification in the mammalian cochlea using somatic force generation underpinned by voltage-dependent conformational changes of the motor protein prestin. However, prestin must be gated by changes in membrane potential on a cycle-by-cycle basis and the periodic compo...

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Detalles Bibliográficos
Autores principales: Johnson, Stuart L., Beurg, Maryline, Marcotti, Walter, Fettiplace, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143834/
https://www.ncbi.nlm.nih.gov/pubmed/21689600
http://dx.doi.org/10.1016/j.neuron.2011.04.024