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Prestin-Driven Cochlear Amplification Is Not Limited by the Outer Hair Cell Membrane Time Constant
Outer hair cells (OHCs) provide amplification in the mammalian cochlea using somatic force generation underpinned by voltage-dependent conformational changes of the motor protein prestin. However, prestin must be gated by changes in membrane potential on a cycle-by-cycle basis and the periodic compo...
Autores principales: | Johnson, Stuart L., Beurg, Maryline, Marcotti, Walter, Fettiplace, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143834/ https://www.ncbi.nlm.nih.gov/pubmed/21689600 http://dx.doi.org/10.1016/j.neuron.2011.04.024 |
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