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A base-calling algorithm for Tm-shifted melting curve SNP assay

BACKGROUND: Tm-shifted melting curve SNP assays are a class of homogeneous, low-cost genotyping assays. Alleles manifest themselves as signal peaks in the neighbourhood of theoretical allele-specific melting temperatures. Base calling for these assays has mostly relied on unsupervised algorithm or h...

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Detalles Bibliográficos
Autores principales: Liang, Kung-Hao, Fen, Jun-Jeng, Chang, Hsien-Hsun, Wang, Hsei-Wei, Hwang, Yuchi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143900/
https://www.ncbi.nlm.nih.gov/pubmed/21884624
http://dx.doi.org/10.1186/2043-9113-1-3