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A base-calling algorithm for Tm-shifted melting curve SNP assay
BACKGROUND: Tm-shifted melting curve SNP assays are a class of homogeneous, low-cost genotyping assays. Alleles manifest themselves as signal peaks in the neighbourhood of theoretical allele-specific melting temperatures. Base calling for these assays has mostly relied on unsupervised algorithm or h...
Autores principales: | Liang, Kung-Hao, Fen, Jun-Jeng, Chang, Hsien-Hsun, Wang, Hsei-Wei, Hwang, Yuchi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143900/ https://www.ncbi.nlm.nih.gov/pubmed/21884624 http://dx.doi.org/10.1186/2043-9113-1-3 |
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