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Downregulation of CD44 reduces doxorubicin resistance of CD44(+)CD24(−) breast cancer cells
BACKGROUND: Cells within breast cancer stem cell populations have been confirmed to have a CD44(+)CD24(−) phenotype. Strong expression of CD44 plays a critical role in numerous types of human cancers. CD44 is involved in cell differentiation, adhesion, and metastasis of cancer cells. METHODS: In thi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143907/ https://www.ncbi.nlm.nih.gov/pubmed/21792314 http://dx.doi.org/10.2147/OTT.S21431 |