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The prognostic impact of K-RAS mutations in adult acute myeloid leukemia patients treated with high-dose cytarabine
BACKGROUND: Activating point mutation of the RAS gene has been generally accepted as an oncogenic event in a variety of malignancies. It represents one of the most common genetic alterations in acute myeloid leukemia (AML). However, little is known about its clinical relevance in the treatment outco...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143910/ https://www.ncbi.nlm.nih.gov/pubmed/21792317 http://dx.doi.org/10.2147/OTT.S12602 |