The prognostic impact of K-RAS mutations in adult acute myeloid leukemia patients treated with high-dose cytarabine

BACKGROUND: Activating point mutation of the RAS gene has been generally accepted as an oncogenic event in a variety of malignancies. It represents one of the most common genetic alterations in acute myeloid leukemia (AML). However, little is known about its clinical relevance in the treatment outco...

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Detalles Bibliográficos
Autores principales: Ahmad, Ebtesam I, Gawish, Heba H, Al Azizi, Nashwa MA, Elhefni, Ashraf M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143910/
https://www.ncbi.nlm.nih.gov/pubmed/21792317
http://dx.doi.org/10.2147/OTT.S12602

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