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Roles of metalloproteinase-3 and aggrecanase 1 and 2 in aggrecan cleavage during human meniscus degeneration

The meniscus plays important roles in proper knee function. It was recently reported that meniscus degeneration was associated with progression of osteoarthritis (OA). However, little is known about the effects of degradative enzymes on the meniscus matrix, primarily collagen type I and aggrecan, du...

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Detalles Bibliográficos
Autores principales: Ishihara, Gintaro, Kojima, Toshihisa, Saito, Yoshimichi, Ishiguro, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143990/
https://www.ncbi.nlm.nih.gov/pubmed/21808676
http://dx.doi.org/10.4081/or.2009.e14