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The Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor

BACKGROUND: Loss of heterozygosity at 18q, which includes the Deleted in Colorectal Cancer (DCC) gene, has been linked to many human cancers. However, it is unclear if loss of DCC is the specific underlying cause of these cancers. The Drosophila imaginal discs are excellent systems in which to study...

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Detalles Bibliográficos
Autores principales: VanZomeren-Dohm, Adrienne, Sarro, Joseph, Flannery, Ellen, Duman-Scheel, Molly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144007/
https://www.ncbi.nlm.nih.gov/pubmed/21672235
http://dx.doi.org/10.1186/1471-213X-11-41