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The Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor
BACKGROUND: Loss of heterozygosity at 18q, which includes the Deleted in Colorectal Cancer (DCC) gene, has been linked to many human cancers. However, it is unclear if loss of DCC is the specific underlying cause of these cancers. The Drosophila imaginal discs are excellent systems in which to study...
Autores principales: | VanZomeren-Dohm, Adrienne, Sarro, Joseph, Flannery, Ellen, Duman-Scheel, Molly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144007/ https://www.ncbi.nlm.nih.gov/pubmed/21672235 http://dx.doi.org/10.1186/1471-213X-11-41 |
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