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Cell clusters overlying focally disrupted mammary myoepithelial cell layers and adjacent cells within the same duct display different immunohistochemical and genetic features: implications for tumor progression and invasion

INTRODUCTION: Our previous studies detected focal disruptions in myoepithelial cell layers of several ducts with carcinoma in situ. The cell cluster overlying each of the myoepithelial disruptions showed a marked reduction in or a total loss of immunoreactivity for the estrogen receptor (ER). This i...

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Detalles Bibliográficos
Autores principales: Man, Yan-gao, Tai, Lisa, Barner, Ross, Vang, Russell, Saenger, Jeffrey S, Shekitka, Kris M, Bratthauer, Gary L, Wheeler, Darren T, Liang, Chang Y, Vinh, Tuyethoa N, Strauss, Brian L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC314413/
https://www.ncbi.nlm.nih.gov/pubmed/14580259