Cytoplasmic p21(WAF1/CIP1 )expression is correlated with HER-2/ neu in breast cancer and is an independent predictor of prognosis

BACKGROUND: HER-2 (c-erbB2/Neu) predicts the prognosis of and may influence treatment responses in breast cancer. HER-2 activity induces the cytoplasmic location of p21(WAFI/CIPI )in cell culture, accompanied by resistance to apoptosis. p21(WAFI/CIPI )is a cyclin-dependent kinase inhibitor activated...

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Detalles Bibliográficos
Autores principales: Winters, Zoë E, Leek, Russell D, Bradburn, Mike J, Norbury, Chris J, Harris, Adrian L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC314414/
https://www.ncbi.nlm.nih.gov/pubmed/14580260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC314414/
https://www.ncbi.nlm.nih.gov/pubmed/14580260

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