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Formation of the Long Range Dpp Morphogen Gradient

The TGF-β homolog Decapentaplegic (Dpp) acts as a secreted morphogen in the Drosophila wing disc, and spreads through the target tissue in order to form a long range concentration gradient. Despite extensive studies, the mechanism by which the Dpp gradient is formed remains controversial. Two opposi...

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Detalles Bibliográficos
Autores principales: Schwank, Gerald, Dalessi, Sascha, Yang, Schu-Fee, Yagi, Ryohei, de Lachapelle, Aitana Morton, Affolter, Markus, Bergmann, Sven, Basler, Konrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144185/
https://www.ncbi.nlm.nih.gov/pubmed/21814489
http://dx.doi.org/10.1371/journal.pbio.1001111