Functional Hair Cell Mechanotransducer Channels Are Required for Aminoglycoside Ototoxicity

Aminoglycosides (AG) are commonly prescribed antibiotics with potent bactericidal activities. One main side effect is permanent sensorineural hearing loss, induced by selective inner ear sensory hair cell death. Much work has focused on AG's initiating cell death processes, however, fewer studi...

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Detalles Bibliográficos
Autores principales: Alharazneh, Abdelrahman, Luk, Lauren, Huth, Markus, Monfared, Ashkan, Steyger, Peter S., Cheng, Alan G., Ricci, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144223/
https://www.ncbi.nlm.nih.gov/pubmed/21818312
http://dx.doi.org/10.1371/journal.pone.0022347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144223/
https://www.ncbi.nlm.nih.gov/pubmed/21818312
http://dx.doi.org/10.1371/journal.pone.0022347

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