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Acidic Environment Leads to ROS-Induced MAPK Signaling in Cancer Cells

Tumor micromilieu often shows pronounced acidosis forcing cells to adapt their phenotype towards enhanced tumorigenesis induced by altered cellular signalling and transcriptional regulation. In the presents study mechanisms and potential consequences of the crosstalk between extra- and intracellular...

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Detalles Bibliográficos
Autores principales: Riemann, Anne, Schneider, Bettina, Ihling, Angelika, Nowak, Martin, Sauvant, Christoph, Thews, Oliver, Gekle, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144229/
https://www.ncbi.nlm.nih.gov/pubmed/21818325
http://dx.doi.org/10.1371/journal.pone.0022445