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Acidic Environment Leads to ROS-Induced MAPK Signaling in Cancer Cells
Tumor micromilieu often shows pronounced acidosis forcing cells to adapt their phenotype towards enhanced tumorigenesis induced by altered cellular signalling and transcriptional regulation. In the presents study mechanisms and potential consequences of the crosstalk between extra- and intracellular...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144229/ https://www.ncbi.nlm.nih.gov/pubmed/21818325 http://dx.doi.org/10.1371/journal.pone.0022445 |