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Postnatal Development of Numbers and Mean Sizes of Pancreatic Islets and Beta-Cells in Healthy Mice and GIPR(dn) Transgenic Diabetic Mice

The aim of this study was to examine postnatal islet and beta-cell expansion in healthy female control mice and its disturbances in diabetic GIPR(dn) transgenic mice, which exhibit an early reduction of beta-cell mass. Pancreata of female control and GIPR(dn) transgenic mice, aged 10, 45, 90 and 180...

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Detalles Bibliográficos
Autores principales: Herbach, Nadja, Bergmayr, Martina, Göke, Burkhard, Wolf, Eckhard, Wanke, Ruediger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144241/
https://www.ncbi.nlm.nih.gov/pubmed/21818396
http://dx.doi.org/10.1371/journal.pone.0022814