Cargando…

β class II tubulin predominates in normal and tumor breast tissues

BACKGROUND: Antimitotic chemotherapeutic agents target tubulin, the major protein in mitotic spindles. Tubulin isotype composition is thought to be both diagnostic of tumor progression and a determinant of the cellular response to chemotherapy. This implies that there is a difference in isotype comp...

Descripción completa

Detalles Bibliográficos
Autores principales: Dozier, James H, Hiser, Laree, Davis, Jennifer A, Thomas, Nancy Stubbs, Tucci, Michelle A, Benghuzzi, Hamed A, Frankfurter, Anthony, Correia, John J, Lobert, Sharon
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC314434/
https://www.ncbi.nlm.nih.gov/pubmed/12927047
http://dx.doi.org/10.1186/bcr631