Cargando…

AAPS Workshop Report: Strategies to Address Therapeutic Protein–Drug Interactions during Clinical Development

Therapeutic proteins (TPs) are increasingly combined with small molecules and/or with other TPs. However preclinical tools and in vitro test systems for assessing drug interaction potential of TPs such as monoclonal antibodies, cytokines and cytokine modulators are limited. Published data suggests t...

Descripción completa

Detalles Bibliográficos
Autores principales: Girish, Sandhya, Martin, Steven W, Peterson, Mark C, Zhang, Lei K., Zhao, Hong, Balthasar, Joseph, Evers, Raymond, Zhou, Honghui, Zhu, Min, Klunk, Lewis, Han, Chao, Berglund, Eva Gil, Huang, Shiew-Mei, Joshi, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144367/
https://www.ncbi.nlm.nih.gov/pubmed/21630127
http://dx.doi.org/10.1208/s12248-011-9285-6