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Osteoblast mineralization requires β1 integrin/ICAP-1–dependent fibronectin deposition
The morphogenetic and differentiation events required for bone formation are orchestrated by diffusible and insoluble factors that are localized within the extracellular matrix. In mice, the deletion of ICAP-1, a modulator of β1 integrin activation, leads to severe defects in osteoblast proliferatio...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144405/ https://www.ncbi.nlm.nih.gov/pubmed/21768292 http://dx.doi.org/10.1083/jcb.201007108 |