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Repeated cleavage failure does not establish centrosome amplification in untransformed human cells

We tested whether cleavage failure as a transient event establishes an incidence of centrosome amplification in cell populations. Five rounds of ∼30% cytochalasin-induced cleavage failure in untransformed human cell cultures did not establish centrosome amplification in the short or long terms. The...

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Detalles Bibliográficos
Autores principales: Krzywicka-Racka, Anna, Sluder, Greenfield
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144409/
https://www.ncbi.nlm.nih.gov/pubmed/21788368
http://dx.doi.org/10.1083/jcb.201101073