Preferential binding of a kinesin-1 motor to GTP-tubulin–rich microtubules underlies polarized vesicle transport

Polarized transport in neurons is fundamental for the formation of neuronal circuitry. A motor domain–containing truncated KIF5 (a kinesin-1) recognizes axonal microtubules, which are enriched in EB1 binding sites, and selectively accumulates at the tips of axons. However, it remains unknown what cu...

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Detalles Bibliográficos
Autores principales: Nakata, Takao, Niwa, Shinsuke, Okada, Yasushi, Perez, Franck, Hirokawa, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144414/
https://www.ncbi.nlm.nih.gov/pubmed/21768290
http://dx.doi.org/10.1083/jcb.201104034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144414/
https://www.ncbi.nlm.nih.gov/pubmed/21768290
http://dx.doi.org/10.1083/jcb.201104034

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